Denu 60mg Injection
Item requires a valid prescription
Manufactured By ALKEM LABORATORIES LTD
Composition DENOSUMAB
Rs 6469.00
MRP Rs 8085.90
(20% OFF)
Includes all taxes
Package SIZE
( 1 PREFILLED SYRINGE(s) OF 1ML )
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Description: Denu 60mg Injection consists of the active ingredient Denosumab. It is a medication used to treat osteoporosis, characterized by weakened bones. It is also prescribed to prevent bone complications in patients with certain types of cancer, such as multiple myeloma and bone metastases. Denu 60mg Injection works by inhibiting a protein called RANK ligand, which plays a role in the breakdown of bone tissue. Studies proved it can significantly increase bone density, reducing fracture risk in postmenopausal women with osteoporosis and patients with cancer-related bone loss. Close monitoring of renal function may be necessary for patients with moderate renal impairment.
Denu 60mg Injection should not be used in individuals with known hypersensitivity or allergic reactions to its components. Adequate calcium and vitamin D supplementation is required to ensure during the treatment. It is not approved for use in children and adolescents. Its safety and effectiveness in pediatric populations have not been established, so its use is contraindicated in individuals under 18. This medication should be used cautiously in individuals with pre-existing hypoparathyroidism, characterized by low parathyroid hormone levels.
Uses / Indications: Denu 60mg Injection is used in the treatment of the following condition: • Osteoporosis • Bone loss due to hormonal therapy in breast or prostate cancer • Multiple myeloma (cancer affects plasma cells in the bone marrow) • Bone metastases (cancer that spreads to bone)
- Product composition:
- DENOSUMAB
Interactions / Warnings: • Denu 60mg Injection should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F).
• Do not freeze it.
• Keep in the original package.
• Keep away from light, moisture, and heat.
• Keep away from children and pets.
• Avoid taking double doses for missed doses.
- Pregnancy interaction:
- Pregnancy (Consult your doctor): The safety of using Denu 60mg Injection during pregnancy has not been established. Limited studies are available regarding the use of this medication in pregnant women, so it is recommended to use caution and consult a doctor before considering its use during pregnancy.
- Expert advice:
- • Inform your doctor about your complete medical history, including previous infections, liver disease, or kidney disease. • Tell your healthcare provider about any allergies or past hypersensitivity reactions. • Seek immediate medical help if you experience severe allergic reactions or serious side effects. • Monitor calcium levels regularly, as Denu 60mg Injection may lower calcium in the blood. • Ensure adequate intake of calcium and vitamin D as advised by your doctor. • Pregnant or breastfeeding women should consult a doctor before using this medication.
- Side Effects:
- Denu 60mg Injection can cause side effects like all medications, although not everyone who takes it will experience them. Serious: • Osteonecrosis of the jaw (severe necrosis or death of jaw cells) • Atypical femoral fractures • Hypocalcemia (low blood calcium levels) Common: • Injection site reactions • Back pain • Musculoskeletal pain • Infections • Abdominal pain • Headache • Hypophosphatemia (low blood phosphate levels)
- How to use:
- Denu 60mg Injection is given as an injection by healthcare professionals. The dosage and duration of treatment will be based on the individual's condition and response to the medication and should be determined by a healthcare provider.
- How it works:
- Denu 60mg Injection has therapeutic effects that include reducing fracture risk, increasing bone mineral density, and improving overall bone health. By inhibiting bone resorption through its action on RANK ligands, this medication helps to strengthen bones and decrease the likelihood of fractures in individuals with osteoporosis or those at high risk. It also increases bone mineral density, an important marker of bone strength. These therapeutic effects contribute to improved bone health and a reduced risk of fractures, ultimately enhancing the quality of life for patients.
- Faq for medicine:
- Q: Can Denu 60mg Injection be used in patients with a history of cancer? A: Denu 60mg Injection is not recommended in patients with a history of certain cancers, such as multiple myeloma or bone metastases. It is important to discuss your medical history and any previous or current cancer diagnoses with your healthcare provider before starting this medication. Q: Can Denu 60mg Injection be used in patients with kidney problems? A: Denu 60mg Injection is primarily eliminated through the kidneys, so caution is advised in patients with severe renal impairment or end-stage renal disease. Your healthcare provider will assess the potential risks and benefits based on your renal function. Q: Can Denu 60mg Injection be used as a treatment for osteoporosis in men? A: Yes, Denu 60mg Injection is approved for the treatment of osteoporosis in men at increased risk of fractures. It can help improve bone density and reduce fracture risk in male patients with osteoporosis. Q: Can Denu 60mg Injection be used in children and adolescents with osteoporosis? A: Denu 60mg Injection is not approved for use in children and adolescents with osteoporosis. The safety and efficacy of this medication have not been established in this population.
- Medicine interaction:
- Inform the doctor about all the medicines, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Denu 60mg Injection and reduce effectiveness by causing undesirable side effects.
